Developing Therapies for Peanut Allergy
نویسندگان
چکیده
منابع مشابه
Developing Therapies for Peanut Allergy
Peanut allergy is an IgE-mediated, persisting immune disorder that is of major concern worldwide. Currently, no routine immunotherapy is available to treat this often severe and sometimes fatal food allergy. Traditional subcutaneous allergen immunotherapy with crude peanut extracts has proven not feasible due to the high risk of severe systemic side effects. The allergen-specific approaches und...
متن کاملImmunotherapy for peanut allergy.
Peanut allergy is one of the commonest food hypersensitivities causing fatal or near-fatal reactions. There is, currently, no preventive treatment and the incidence of severe allergic reactions during peanut desensitisation has limited its clinical use. Anti-immunoglobulin E therapy has been shown to be effective in preventing peanut-induced reactions but it does not result in long-term toleran...
متن کاملSignificance of Peanut Allergy
The prevalence of peanut allergy (PA) in Africa is unknown but anecdotal reports suggest the prevalence to be lower than that experienced in developed countries, which report a prevalence of approximately 1.5%. Countries in Africa and Asia, as well as Israel, where the early consumption of high-dose peanut protein is routinely practised, have enjoyed a low prevalence of peanut allergy, e.g. 0.0...
متن کاملPeanut Allergy: An Overview
: Peanut allergies have been increasing in prevalence in most industrialized countries. Onset is typically in early childhood, with a trend towards earlier ages of presentation. The allergy is lifelong in most affected children, although 15-22% will outgrow their peanut allergy, usually before their teenage years. Manifestations of peanut allergy range from mild to severe, and risk factors pred...
متن کاملPeanut consumption in infants at risk for peanut allergy.
BACKGROUND The prevalence of peanut allergy among children in Western countries has doubled in the past 10 years, and peanut allergy is becoming apparent in Africa and Asia. We evaluated strategies of peanut consumption and avoidance to determine which strategy is most effective in preventing the development of peanut allergy in infants at high risk for the allergy. METHODS We randomly assign...
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ژورنال
عنوان ژورنال: International Archives of Allergy and Immunology
سال: 2014
ISSN: 1018-2438,1423-0097
DOI: 10.1159/000369340